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Version imprimable

Marc A. Gauthier

Better "Biologics" – Better Therapies


44. J Abdul-Hadi, MA Gauthier, M Packirisamy

Silicon-free, low-loss and high contrast polymer multimode waveguides

Journal of Micromechanics and Microengineering, 2017, Accepted


43. F Ambriz Vargas, G Kolhatkar, M Broyer, A Hadj Youssef, R Nouar, A Sarkissian, R Thomas, C Gomez-Yanez, MA Gauthier, A Ruediger

A CMOS compatible, ferroelectric tunnel junction

ACS Applied Materials and Interfaces, 2017, 9, 13262


42. Y Gong, D Andina, S Nahar, J-C Leroux, MA Gauthier

Releasable and Traceless PEGylation of Arginine-rich Antimicrobial Peptides

Chemical Science, 2017, 8, 4082


41. X Ropagnol, X Chai, SM Raeis-Zadeh, S Safavi-Naeini, M Kirouac-Turmel, M Bouvier, C-Y Côté, M Reid, MA Gauthier, T Ozaki

Influence of gap size on intense THz generation from ZnSe interdigitated large aperture photoconductive antennas

IEEE Journal of Selected Topics in Quantum Electronics, 2017, 23, 3800808


40. F Ambriz-Vargas, R Thomas, A Sarkissian, C Gomez-Yáñez, MA Gauthier, A Ruediger
Tunneling electroresistance effect in a Pt/Hf0.5Zr0.5O2/Pt structure
Applied Physics Letters, 2017, 110, 093106


39. S Veltri, E Sokullu, M Barbiero, MA Gauthier, P Antici

Synthesis and characterization of thin-transparent nanostructured films for surface protection

Superlattices and Microstructures, 2017, 101, 209





38. A Polomska, MA Gauthier, J-C Leroux

In vitro and in vivo evaluation of PEGylated layer-by-layer polyelectrolyte-coated paclitaxel nanocrystals

Small, 2016 doi: 10.1002/smll.201602066


37. F Ambriz-Vargas, R Nouar, G Kolhatkar, A Sarkissian, R Thomas, C Gomez-Yanez, MA Gauthier, A Ruediger

RF-magnetron sputtering deposition of ultra-thin Hf0.5Zr0.5O2 films for non-volatile memory applications

Materials Today, 2016, Accepted


36. X Ropagnol, M Khorasaninejad, M Raeiszadeh, S Safavi-Naeini, M Bouvier, CY Côté, A Laramée, M Reid, MA Gauthier, T Ozaki

Intense THz pulses with large ponderomotive potential generated from large aperture photoconductive antennas

Optics Express, 2016, 24, 11299


35. Y Zhao, AC Tavares, MA Gauthier

Nano-engineered electro-responsive drug delivery systems

Journal of Materials Chemistry B, 2016, 4, 3019


34. JD Schultz, M Patt, S Basler, H Kries, D Hilvert, MA Gauthier, J-C Leroux

Site-specific polymer conjugation stabilizes therapeutic enzymes in the gastro-intestinal tract

Advanced Materials, 2016, 28, 1455




33. Y Chen, C Yang, M Zhang, Y Liu, Zhang, T Li, A Gauthier, Y Zhao, C Wu 

The Interplay of Disulfide Bonds, α-Helicity, and Hydrophobic Interactions Leads to Ultrahigh Proteolytic Stability of Peptides 

Biomacromolecules, 2015, 16, 2347


32. M Liu, J-C Leroux, MA Gauthier

Conformation–function relationships for the comb-shaped polymer pOEGMA

Progress in Polymer Science,  2015, 48, 111


31. JD Schultz, MA Gauthier, J-C Leroux

Improving oral drug bioavailability with polycations?

European Jouranl of Pharmaceutics and Biopharmaceutics, 2015, 97B, 427


30. Y Gong, J-C Leroux, MA Gauthier

Releasable Conjugation of Polymers to Proteins

Bioconjugate Chemistry, 2015, 26, 1172


29. PM Klein, K Müller, C Gutmann, P Kos, A Krhac Levacic, D Edinger, M Höhn, J-C Leroux, MA Gauthier, E Wagner

Twin disulfides as opportunity for improving stability and transfection efficiency of oligoaminoethane polyplexes

Journal of Controlled Release, 2015, 205, 109




28. M Liu, P Johansen, F Zabel, J-C Leroux, MA Gauthier

Semi-permeable coatings fabricated from comb-polymers efficiently protect proteins in vivo

Nature Communications, 2014, 5, 5526


27. L Brülisauer, MA Gauthier, J-C Leroux

Disulfide-Containing Parenteral Delivery Systems and Their Redox-Biological Fate

Journal of Controlled Release, 2014, 195, 147


26. L Brülisauer, G Valentino, S Morinaga, K Cam, J Thostrup Bukrinski, MA Gauthier, J-C Leroux

Bio-reduction of redox-sensitive albumin conjugates in FcRn-expressing cells

Angewandte Chemie International Edition, 2014, 53, 8392


25. MA Gauthier

Redox-responsive drug delivery

Antioxidants & Redox Signalling, 2014, 21, 705


24. K Fuhrmann, MA Gauthier, J-C Leroux

Targeting of injected drug nanocrystals

Molecular Pharmaceutics, 2014, 11, 1762


23. O Shishkan, M Zamfir, MA Gauthier, HG Börner, JF Lutz

Complex Single-chain Polymer Topologies locked by Positionable Twin Disulfide Cyclic Bridges

Chemical Communications, 2014, 50, 1570




22. K Fuhrmann, AK Połomska, C Aeberli, B Castagner, MA Gauthier, J-C Leroux

Modular design of redox-responsive stabilizers for nanocrystals

ACS Nano, 2013, 7, 8243


21. C Wu, S Wang, L Brülisauer, J-C Leroux, MA Gauthier

Broad control of disulfide stability through microenvironmental effects and analysis in complex redox environments

Biomacromolecules, 2013, 14, 2383


20.  G Fuhrmann, A Grotzky, R Lukić, S Matoori, H Yu, P Luciani, P Walde, AD Schlüter, MA Gauthier, J-C Leroux

Sustained gastrointestinal activity of dendronized polymer–enzyme conjugates

Nature Chemistry, 2013, 5, 582

Featured: Nature Chemistry News and Views 2013, 5, 557; SciBX5(46); doi:10.1038/scibx.2013.707 on nature.com/scibx; Polymer and Colloid Highlights, Chimia 2013, 67, 685


19. M Liu, P Tirino, M Radivojevic, DJ Phillips, MI Gibson, J-C Leroux, MA Gauthier

Molecular sieving on the surface of a protein provides protection without loss of activity

Advanced Functional Materials. 2013, 23, 2007




18.  L Brülisauer, N Kathriner, M Prenecaj, MA Gauthier, J-C Leroux

Tracking the Bio-reduction of Disulfide-Containing Cationic Dendrimers

Angewandte Chemie International Edition, 2012, 51, 12454

Featured: Wiley: Hot topic in drug delivery Nov 2012


17. C Wu, J-C Leroux, MA Gauthier

Twin disulfides for orthogonal disulfide pairing and the directed folding of multi-cyclic peptides

Nature Chemistry, 2012, 4, 1044

Featured: SciBX5(46); doi:10.1038/scibx.2012.1219 on nature.com/scibx


16.  M-H Dufresne, E Marouf, Y Kränzlin, MA Gauthier, J-C Leroux

Lipase is an essential additive for in vitro optimization of organogels

Molecular Pharmaceutics, 2012, 9, 1803


15.  K Fuhrmann, JD Schulz, MA Gauthier, J-C Leroux

PEG nano-cages as non-sheddable stabilizers for drug nanocrystals

ACS Nano, 2012, 6, 1667




14. C Wu, C Belenda, J-C Leroux, MA Gauthier

Interplay of chemical microenvironment and redox environment on thiol–disulfide exchange kinetics

Chemistry – A European Journal, 2011, 17, 10064

Featured: Wiley: Hot topic in drug delivery Aug 2011 and Chimia, the magazine of the Swiss Chemical Society.


13.  N Bertrand, MA Gauthier, C Bouvet, P Moreau, A Petitjean, J-C Leroux, J Chain

New pharmaceutical applications for macromolecular binders

Journal of Controlled Release, 2011, 155, 200


12.  MA Gauthier, M Ayer, J Kowal, FR Wurm, H-A Klok

Arginine-specific protein modification using α-oxo-aldehyde functional polymers prepared by atom transfer radical polymerization

Polymer Chemistry, 2011, 2, 1490


11.  MA Gauthier and H-A Klok

Arginine-specific modification of proteins with polyethylene glycol

Biomacromolecules, 2011, 12, 482




10.  MA Gauthier* and H-A Klok

Polymer–protein conjugates: an enzymatic activity perspective

Polymer Chemistry, 2010, 1, 1352

Featured: on cover




9.  MA Gauthier, MI Gibson, H-A Klok

Synthesis of functional polymers by post-polymerization modification

Angewandte Chemie International Edition, 2009, 48, 48

Most accessed paper in December 2008


8.  MA Gauthier, Z Zhang, XX Zhu

New dental composites containing multimethacrylate derivatives of bile acids

ACS Applied Materials and Interfaces, 2009, 1, 824

Featured: National Geographic News, Reuters, Berliner Zeitung, Popular Science, Fox News, The Times, Science Daily, Canadanews.net




7.  MA Gauthier and H-A Klok

Peptide/protein-polymer conjugates: synthetic strategies and design concepts

Chemical Communications, 2008, 2591




6.  MA Gauthier, P Simard, Z Zhang, XX Zhu

Bile acids as constituents for dental composites: in vitro cytotoxicity of (meth)acrylate and other ester derivatives of bile acids

Journal of the Royal Society Interface, 2007, 4, 1145




5.  MA Gauthier, I Stangel, TH Ellis, XX Zhu

Oxygen inhibition in dental resins

Journal of Dental Research, 2005, 84, 725


4.  M-H Dufresne, MA Gauthier, J-C Leroux

Thiol-functionalized polymeric micelles: from molecular recognition to improved mucoadhesion

Bioconjugate Chemistry, 2005, 16, 1027


3.  XX Zhu, JH Zhang, MA Gauthier, FS Meng, JT Luo, FS Brisse

Large uniformly-sized polymer beads for use as solid phase supports prepared by ascending polymerization

Journal of Combinatorial Chemistry, 2005, 8, 79


2.  MA Gauthier, I Stangel, XX Zhu, TH Ellis

A new method for quantifying the intensity of the C=C band of dimethacrylate dental monomers in their FTIR and Raman spectra

Biomaterials, 2005, 26, 6440




1.  MA Gauthier, JT Luo, D Calvet, C Ni, XX Zhu, M Garon, MD Buschmann

Degree of crosslinking and mechanical properties of crosslinked poly(vinyl alcohol) beads for use in solid-phase organic synthesis

Polymer, 2004, 45, 8201





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