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Simona Stäger

Immunology of infectious diseases

The main interest of the laboratory lies in understanding how the adaptive immune response is regulated during chronic infections. We are currently focussing on three topics:

 

1. The development of effector and memory CD8 T-cell responses during chronic infections

We are mainly interested in molecular pathways governing early priming events, induction and maintenance of effector CD8 T-cell responses, and the generation of memory cells.

 

2. The regulation of CD4 T cell responses during chronic infection

Particular interest is given to immune suppressive pathways operating during chronic infections and aiming at inhibiting CD4 T cell responses.

 

3. The mechanisms of induction of hypergammaglobulinemia by the protozoan parasite Leishmania donovani

We seek to identify pathways triggered by L. donovani that lead to polyclonal B cell activation and ultimately to hypergammaglobulinemia.

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Simona Stäger et la lutte aux maladies chroniques ...

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La professeure Simona Stäger

La professeure Simona Stäger

Simona Stäger, professeure au Centre INRS-Institut Armand-Frappier

Simona Stäger, professeure au Centre INRS-Institut Armand-Frappier